Sector · United Kingdom

AI Infrastructure & Chips startups in the UK

The picks-and-shovels layer of AI: GPU cloud, data platforms, ML infrastructure and AI chips. British infrastructure companies are building the compute the rest of the ecosystem runs on.

15
Companies
270
UK & remote roles open
06AI Infra

HelixDB

Open-source graph-vector database giving AI agents low-latency memory and relationship-aware retrieval for RAG (YC X25).

LondonSeed
Careers →helix-db.com
08ML Infra

Plexe

Open-source agents that build, evaluate and deploy production-grade predictive ML models from a prompt (YC X25).

LondonSeed
Careers →plexe.ai
09ML Infra

mlop

Open-source, performant experiment tracking for ML training, a Weights & Biases alternative with API compatibility (YC X25).

LondonSeed
Careers →mlop.ai
10ML Infra

Fuzzy Labs

Open-source MLOps consultancy building bespoke machine-learning infrastructure for teams that want to avoid proprietary vendor lock-in.

ManchesterBootstrapped
6 UK rolesfuzzylabs.ai
11AI Infrastructure

Callosum

Founded by two Cambridge neuroscience PhDs; systems software that breaks an AI workload into tasks and routes each to the model and chip best suited to it, so heterogeneous silicon can stand in for banks of identical GPUs. First equity investment from the UK's Sovereign AI Fund.

LondonSeed
18 UK rolescallosum.com
12AI Chips

Fractile

Inference silicon that puts compute and memory on the same die, skipping the DRAM bottleneck; claims LLMs run far faster at a fraction of the running cost. London HQ plus a Bristol hardware engineering site, with first datacentre chips due 2027.

LondonSeries B
47 UK rolesfractile.ai
13AI Infrastructure

Fireworks AI

San Mateo inference platform for open models, serving 40tn+ tokens a day; valued at $17.5bn in July 2026 and now standing up an EMEA team in London.

LondonSeries D
7 UK rolesfireworks.ai
14AI Chips

Singular Photonics

University of Edinburgh spin-out building single-photon (SPAD) image sensors with compute on the chip, for machine vision, physical AI and medical imaging; its founding professor designed the first SPAD sensor on silicon CMOS.

EdinburghSeed
Careers →singularphotonics.com
15AI Infrastructure

Modal

New York serverless cloud for AI workloads — custom model inference, fine-tuning, RL and agentic sandboxes — scaling from zero to hundreds of GPUs on containers defined in code. Raised $355m at a $4.65bn valuation in May 2026 and is now opening a London office.

LondonSeries C
4 UK rolesmodal.com
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